3 Cardiac arrhythmias affected 2-11% of participants on retatrutide versus 2% on placebo, but none were serious
[9] Tirzepatide (Mounjaro) is recommended by NICE (TA820) for adults with type 2 diabetes
Scheme 5
Expected Price Range Based on comparables (Wegovy, Zepbound): private UK clinics: high 100s to 1000+ per month NHS pricing: discounted, depending on approval telehealth clinics: variable based on distributor agreements Why It Will Be Expensive high R&D cost large clinical programs complex peptide synthesis limited initial supply UK Affordability When retatrutide UK access eventually arrives: private clinics will dominate the early market NHS entry may take longer limited stock may keep the price high for years Coming Off Retatrutide (What Happens After Retatrutide) Search interest in coming off retatrutide is rising because GLP-1 discontinuation data shows clear patterns of weight regain once appetite signals return

Key takeaways: 27% of respondents noticed changes to their menstrual cycle since starting GLP-1 medication for weight loss Respondents with PCOS were more likely to experience cycle changes, and 43% of this group reported noticing changes to their menstrual cycle The most commonly reported cycle changes were more predictable periods, more frequent periods, and shorter periods GLP-1 medications like semaglutide (Ozempic) and tirzepatide (Mounjaro) have traditionally been used to treat diabetes
Eden also includes 24/7 coaching access and community support at no extra charge, providing lifestyle guidance that helps patients develop sustainable habits